Zinc Citrate | A Multifunctional Oral Care Ingredient
Zinc citrate is very versatile. First, it is a common zinc supplement that can be used to supplement the zinc needed by the body. Secondly, zinc citrate can be used to treat some diseases, such as oral ulcers, stomach ulcers, diarrhea and so on.
Zinc citrate is very versatile. First, it is a common zinc supplement that can be used to supplement the zinc needed by the body. Secondly, zinc citrate can be used to treat some diseases, such as oral ulcers, stomach ulcers, diarrhea and so on. In addition, zinc citrate can also be used to improve the reproductive performance and growth of animals. Today, let's talk about the use of zinc citrate in the mouth.
INCI Name: Zinc citrate
English name: ZINC CIRATE
CAS No: 546-46-3
Molecular weight: 610.37
Molecular formula :(C6H5O7)2 Zn3 · 2 H2O
Zinc citrate is a white powder. Almost odorless, slightly soluble in water, soluble in diluted acids, almost insoluble in ethanol (96%).
The role of zinc citrate in oral cavity
1. Inhibit oral bacteria and control dental plaque
Zinc citrate, the active substance, mainly intervenes in the second and third stages of dental plaque growth, reduces the formation of dental plaque by inhibiting the growth of oral bacteria. There are many antibacterial mechanisms of zinc compounds, including the theory of zinc ion dissolution, contact and nano-antibacterial. Zinc lemonate is mainly based on the theory of antibacterial dissolution of zinc ion, and the dissolved zinc ion has antibacterial effect in contact with bacteria
Clinical trials found that after using 1% zinc citrate toothpaste, the anaerobic bacteria and streptococcus indices of dental plaque, oral mucosa, tongue and saliva in the experimental group were reduced by 24% to 52% compared with the baseline, which was more significant than the control group. At the same time, the biofilm generated in situ on hydroxyapatite tablets could also be significantly inhibited.
Clinical trials have found similar results: After 14 days of brushing with 1% zinc citrate toothpaste, the number of anaerobic bacteria in plaque, tongue, buccal mucosa and saliva decreased by 38.56%, 23.57%, 26.24% and 29.1%, respectively, which was significantly different from the control group. This shows that the use of zinc citrate toothpaste can effectively reduce the bacteria in all parts of the mouth.
2. Relieve breath problems
The use of zinc citrate toothpaste, oral zinc ion concentration can be maintained in a certain range for a period of time, its flavor removal effect is divided into two sides: on the one hand, zinc ion can inhibit the growth of the source bacteria of bad breath, reduce the production of unpleasant gas; On the other hand, through the synthesis of zinc ions and sulfhydryl groups, some unpleasant gases become non-volatile products, reducing the emission of unpleasant gases.
3, anti-tooth stones
Zinc dissociation can effectively relieve or reduce the formation of dental stones, and can act in the mineralization process of calcium phosphonate
Clinical trials showed that toothpaste containing 0.5% zinc citrate trihydrate could significantly inhibit dental calculus compared with control.
Toothpaste containing 0.5% zinc citrate trihydrate can effectively deliver to the tooth surface and plaque, which can help suppress plaque.
4. Relieve gum problems
The role of zinc citrate in alleviating gum problems is mainly reflected in two aspects:
① Inhibit dental plaque and the development of dental calculus, especially the invasion of subgingival calculus to gingival tissue;
② Inhibit the growth of gingivitis pathogenic bacteria (porphyromonas gingivalis, clostridium nucleatum and prevotella intermedia, etc.), reduce the production of toxic substances, and alleviate gingival periodontal problems.
Recommended dosage: 0.5-1%
In the toothpaste formulation, the content of zinc citrate is generally between 0.5% and 2%, in order to inhibit oral pathogens, control dental plaque, relieve oral gas problems, anti-dental calculus, relieve gum problems and other effects