Innovation in Dual Large-Port Cell Factories

27 Mar.,2025

In the modern fields of biopharmaceuticals and vaccine production, the design innovations of cell factories, which serve as crucial cell culture containers, are essential for enhancing production efficiency and product quality.

 

In the modern fields of biopharmaceuticals and vaccine production, the design innovations of cell factories, which serve as crucial cell culture containers, are essential for enhancing production efficiency and product quality. In recent years, the dual large-port design has gained significant attention and application as a key technological advancement.

The dual large-port design of cell factories refers to the incorporation of two larger-diameter ports in the structure, used respectively for the inflow and outflow of liquids. Compared to small-diameter designs, this innovative approach offers multiple advantages:

Enhanced Liquid Handling Efficiency: The dual large-port design significantly increases the speed of liquid filling and harvesting. The larger ports can accommodate more liquid, reducing operation time during filling and thus improving production efficiency.

Innovation in Dual Large-Port Cell Factories

Reduction of Bubble Formation: The larger port design effectively decreases the likelihood of bubble formation. In cell culture processes, the presence of bubbles can negatively impact cell growth and product quality. The dual large-port design helps mitigate this issue, promoting stable cell growth.Improved Gas Exchange Capacity: The dual large-port design enhances the efficiency of gas exchange within the cell factory. This is particularly important for high-density cell cultures, as it provides more effective oxygen supply and carbon dioxide removal, supporting better cell growth and product synthesis.

The dual large-port design of cell factories is not just a technological innovation, but also a crucial step towards improving production efficiency and product quality. Its numerous advantages have led to its widespread adoption in biopharmaceuticals, vaccine production, and other biotechnology fields. With superior operational performance and technical innovation, it has become an ideal choice for many manufacturers and research institutions.